Gary Null, Ph.D.
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 Vitamins, Nutrients & Herbal Supplements
Suggested Dosages
Dosaged Based on Peer-Review Journal Articles*
B Complex
50 mg
10-200 mg
B6
25-75 mg
50-200 mg
Folic Acid
400 meg
2.5-35 mg
100 meg
1,000 mcg-3 mg
Choline
500 mg
500 mg-16,000 mg
Vitamin E
400-800 IU
30-4,800 mg
L-Methionine
500 mg
2,000-10,000 mg
Vitamin C
2,000-15,000 mg
30-17,000 mg
Silybum Marianum
50 mg
140-600 mg
Garlic
500 mg 4xday
3,000-10,000 mg
Evening Primrose Oil
500 mg 2xday
3,000-6,000 mg
Fish oil lipids
1,000 mg
2,600-24,000 mg
Ginkgo Biloba
60-120 mg
50-600 mg
Lecithin
5 gm
0. |
Textbook of Natural Medicine 2nd Edition Volume 2Michael T. Murray, ND
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| A2 production, reduced elevated systolic blood pressure, reduced triglyceride levels, and caused small, but statistically significant, increases in HBAlc and total cholesterol.83 The benefits were retained and the deleterious effects reduced at the lower dosage.
In another study, a 96% pure EPA product at a dose of 900 mg/day for 8 weeks reduced platelet aggregation due to platelet-activating factor, but had little effect on diabetes regulation, lipid levels, and blood rheology.84 In contrast, 1,800 mg/day for 8 weeks reduced platelet aggregation, but LDL cholesterol increased significantly. |
Ronald Klatz and Robert Goldman
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 Magnesium protects the heart in a number of ways:
• Magnesium acts as a gatekeeper, regulating the amount of calcium needed to maintain a steady heartbeat. Thus a deficiency in magnesium can produce heartbeat abnormalities that may lead to death.
• Magnesium prevents spasm of the coronary artery. As we saw when we looked at selenium, arterial spasms can be set off by tobacco smoke, alcohol, fatty foods, and stress; such spasms can lead to stroke and heart attack.
• Magnesium inhibits the formation of blood clots. According to Dr. |
Janet Zand, LAc, OMD, Allan N. Spreed, MD, CNC, James B. LaValle, RPh, ND
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 For detailed information about this program, you can consult The Multiple Sclerosis Diet Book by Dr. Swank and Barbara Brewer Dugan, R.N. (Doubleday, 1987).
NUTRITIONAL SUPPLEMENTS
¦ Take a high-potency multivitamin and mineral supplement daily.
¦ To make sure of complete utilization of all important nutrients, take a full-spectrum digestive-enzyme supplement providing 5,000 international units of lipase, 2,500 international units of amylase, and 300 international units of protease, plus 500 to 1,000 milligrams of pancreatin, with each meal. |
Textbook of Natural Medicine 2nd Edition Volume 1Michael T. Murray, ND
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| Table 68.2 lists boron's impact on selected hormones in either animals or humans. Some of these interactions have only been demonstrated in animal models (*) while others have not been demonstrated unequivocally to date in all age and gender segments of a human population (**).
Table 68. |
John R. Smythies
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| The potent antioxidant NAC can be given adequately by means of an aerosol spray. Winklhofer-Roob et al. have shown that patients with this disease who have low blood levels of vitamin C also have high blood indices of inflammation (MDA and TGFoc levels), whereas those with high levels of vitamin C have "clearly lower values" of these indices of inflammation [232]. |
Textbook of Natural Medicine 2nd Edition Volume 1Michael T. Murray, ND
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| P5P in order to optimize the interrelated pathways of homocysteine metabolism.
Pyridoxal 5'-phosphate
P5P is the active coenzyme form of vitamin B6. This cofactor is involved in a myriad biological processes, including the trans-sulfuration pathway of homocysteine. This degradation pathway involves a two-step process, resulting in the formation of cystathionine and its subsequent cleavage to cysteine. |
Ralph Moss, PhD
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 Follow-up research will take a decade or more, if it ever happens, and if history is any guide, will be followed by yet more calls for further research. There is no end to research. In the meantime, however, millions more people will die of cancers that might have been prevented with a pill that costs pennies. Wouldn't it make more sense to say that our provisional recommendation is that every adult take 200 micrograms per day? I think Dr. Robert Atkins' acerbic comment is fully justified: "Needless to say, drug studies aren't greeted with such hesitation so routinely. |
Schuyler W. Lininger, Jr. DC
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 Are There Any Side Effects or Interactions? Refer to the individual supplement for information about any side effects or interactions.
Herbs That May Be Helpful
Bilberries (p. 396), a close relative of blueberries, are high in a bioflavonoid complex known as anthocyanosides. Anthocyanosides speed the regeneration of rhodopsin, the purple pigment that is used by the rods in the eye for night vision.2 This makes bilberry a possible first line of defense for those with poor night vision. |
| A recent double-blind placebo-controlled study found that a supplement of 5 grams of creatine plus 1 gram of glucose taken 4 times per day for 5 days followed by twice a day for 51 days significantly lowered serum total cholesterol (p. 79) and triglycerides (p. 85), but did not change either LDL or HDL cholesterol, in both men and women.18
Where Is It Found?
Creatine is produced naturally in the human liver, pancreas, and kidneys. It is concentrated primarily in muscle tissues, including the heart. |
| Lysine has many functions in the body because it is incorporated into many proteins, each of which is used by the body for a variety of purposes. Lysine interferes with replication of herpesviruses and is therefore often prescribed by nutritionally oriented doctors to people with cold sores (p. 39) or genital herpes. A review of the research trials investigating the effects of lysine on people with cold sores shows that most though not all trials support the use of lysine.4
Where Is It Found?
Brewer's yeast, legumes, dairy, wheat germ, fish, and meat all contain significant amounts of lysine. |
| Inositol Has Been Used in
Connection with the Following Conditions*
Ranking
Health Concerns
Other
Anxiety (p. 14) Depression (p. 50) Diabetes (p. 53)
*Referto the Individual Health Concern for Complete Information
How Much Is Usually Taken?
Most people do not need to take inositol. In addition, the small amounts commonly found in multi-vitamin supplements (p. 314) are probably unnecessary and ineffective. Nutritionally oriented doctors sometimes suggest 500 mg twice per day.
Are There Any Side Effects or Interactions? |
| Turner's syndrome—a disease linked with glucose intolerance.1
Chromium may also play a role in increasing HDL (the "good" cholesterol),2 yet lowering overall cholesterol levels (p. 79).3
Chromium, in a form called chromium picolinate, has been studied for its potential role in altering body composition. Preliminary research in animals4 and humans5,6 suggested that chromium picolinate increases fat loss and lean muscle tissue gain. |
Dharma Singh Khalsa, M.D.
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 He was already taking a relative abundance of nutritional supplements, but like many people, he was taking some supplements he didn't need, and was not taking some that he did need. He was also taking too many of his supplements at the end of the day, instead of in the morning. I recommended that he "front-load" his supplements early in the day, so that he could get more energy from them during his workday.
J.R. enjoyed doing the mind/body exercises. He had never tried anything quite like them before, and was open to anything new that might, as he put it, "take me to the next level. |
Committee on Diet, Nutrition, and Cancer, Assembly of Life Sciences National Research Council
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 N-nitrososarcosine in the esophagus and fore-stomach of Sprague-Dawley rats. They observed that tumor incidence in the group supplemented with molybdenum (2 mg/liter drinking water) was lower than that in the control group, whose diet contained a molybdenum concentration of 26 pg/kg diet.
Molybdenum In the form of molybdenum oxide was shown to induce a significant increase in the number of lung adenomas in Strain A mice (Stoner et al., 1976). Molybdenum as potassium molybdate and ammonium molybdate was positive in Bacillus subtilus rec assay (Nishioka, 1975). |
Schuyler W. Lininger, Jr. DC
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| Glutamine (p. 300), an amino acid, is the principal source of energy for cells that line the small intestine and stomach. Years ago, glutamine was reported to help people with peptic ulcer in a preliminary trial.28 Glutamine has also prevented stress ulcers triggered by severe burns in another preliminary report.29 Despite the limited amount of published research, some nutritionally oriented doctors suggest 500-1,000 mg of glutamine taken 2 to 3 times per day to help people overcome peptic ulcers.
Research has shown that bioflavonoids (p. 271)—such as quercetin (p. |
John R. Smythies
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| A diet rich in dark green leafy vegetables and/or supplements with lutein and zeaxanthin, and with tomatoes and/or supplements of lycopene, may help protect against this form of blindness.
RESPIRATORY
DISEASES The lung is at risk of oxidative stress because of the large amounts of oxygen that pass through it when we breathe. Oxidative stress in the lung leads to damage to the cell membranes, inflammation, and bronchoconstriction.
ASTHMA. Asthma is a chronic respiratory disorder that results in constriction of the bronchi and difficulty in breathing. |
Textbook of Natural Medicine 2nd Edition Volume 2Michael T. Murray, ND
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| Section 2).
Bowel toxemia
A number of gut-derived toxins are implicated in the development of psoriasis, including endotoxins (cell wall components of Gram-negative bacteria), streptococcal products, Candida albicans, yeast compounds, and IgE and IgA immune complexes.9-11 These compounds lead to increases in cyclic GMP levels within skin cells, thereby increasing the rate of proliferation dramatically. Candida albicans overgrowth in the intestines (chronic candidiasis) may play a major role in many cases.
A diet low in dietary fiber is associated with increased levels of gut-derived toxins. |
H.J. Roberts, M.D.
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 Other Possible Pathologic Changes
Pathologic changes induced by excessive amino acid administration have been termed "amino acid imbalance," "amino acid antagonism," and "amino acid toxicity" (Brown 1967).
Excessive phenylalanine may interfere with the ability of tissues other than the brain to metabolize amino acids.
• This is most impressively demonstrated in children with PKU.
• After four weeks of phenylalanine administration, rats develop weight loss, marked pancreatic and liver changes, thickening of the skin (hyperkeratosis), and inhibition of sperm production (Klavins 1967). |
Elson M. Haas, M.D.
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 Further research is required, but it appears that molybdenum is very important for optimum health and longevity.
Selenium has become one of the most exciting nutrients of the 1970s and 1980s. Once classified solely as a toxic mineral, it is now regarded as an essential one, needed in small daily amounts. Selenium functions as a component of the enzyme glutathione peroxidase, which accounts for its antioxidant function and thus its important contribution to the prevention of the twentieth-century plagues, cancer and cardiovascular disease. |
Attaining Medical Self SufficiencyDuncan Long
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| He noted that the "striking reduction in illness" he had seen in his study was of "considerable clinical and public-health importance."
Chandra wrote that, "in spite of eating a balanced diet, it seems about 25 percent of elderly people have nutrient deficits without any symptoms. |
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