J. E. Williams, O.M.D.
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 If they are low, consider natural hormone replacement or supplementation.
Hormones work synergistically with each other in a harmonious interplay of molecules. That is exactly the reason that doctors practicing functional medicine with natural biological medications can get better results with lower dosages. Hormones work well together.
Some examples of this are the following: Melatonin helps both thymus and thyroid function, HGH and thyroid help each other's function, DHEA can raise HGH levels. |
| Microflora are as integral to effective cleansing and health as is a good diet; microflora supplementation with acidophilus bacteria is often a part of a detoxification and rejuvenation program.
Blood and Lymphatic System: Traditional nature cure doctors knew that "cure'' meant the complete replacement of diseased cells with healthy ones. To achieve this, they emphasized that cleansing the blood was the first goal of detoxification therapy. Without healthy and clean blood, the cells can never be renewed. |
| Vitamin C supplementation (as little as 500 mg) in particular appears to significantly raise glutathione levels. Michael Murray, N.D., a naturopathic physician and a leading authority on natural medicine, strongly agrees and recommends that doctors avoid the use of the expensive glutathione supplements, suggesting that patients stay with vitamin C. The amino acid L-methionine and its activated form, S-adenosylmethionine (SAM), also raise glutathione levels.
Many toxic substances deplete glutathione including common over-the-counter drugs, especially acetaminophen (Tylenol). |
| Though healthy people do not need glutamine supplementation, it is useful for general immune weakness and for those losing muscle mass due to illness.
Therapeutic dosages can be as high as 40 g per day, but a basic range is from 500-2,000 mg. During periods of stress, when you are engaging in heavy exercise, and/or treating bowel disease, the dosage can climb upward to 4,000-8,000 mg (4-8 g). The optimal dosage is not yet known, but there are no toxic side effects. It is best taken in the powdered form, mixed directly into water or juice. |
| In these cases, arginine supplementation should not be used and one should even avoid arginine-containing foods such as nuts, cheeses, and chocolate.
Otherwise, arginine is a safe substance, free from side effects; however, since arginine works synergistically with ornithine to stimulate growth hormone, some doctors warn against its use in diabetes, as the growth hormone increase it can cause may overwork the pancreas. Arginine should also be avoided in cancer patients, as high dosages have been shown to increase cancer cell growth. |
Ronald L. Hoffman, M.D.
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 While commercial supplementation (in foods like milk and dairy products) represents one source of this important vitamin, it is also manufactured by the skin in the presence of sunlight.
Some Guidelines on Taking Supplements
• If you decide to take antioxidants, remember that there are many other antioxidants in vegetables and fruits that you won't be able to get in a pill; eat at least five servings of these antioxidant rich foods per day.
• Don't rely on your multivitamin to provide you with sufficient antioxidants, even if the label says "contains the full antioxidant group. |
Patricia Hausman & Judith Benn Hurley
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 Greenwald notes supplementation with both vitamins E and C helps to reduce the formation of gene-altering mutagens in the intestinal tract. He, like many of his fellow scientists, suspects that by keeping those mutagens at bay, the cancer process can be discouraged.
Of course, no discussion of nutrition would be complete without mentioning selenium. Like the three vitamins, this mineral also wears the antioxidant hat. Dr. |
Earl Mindell
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 As for amino acid supplements and their value to you as an individual, I'd suggest looking over sections 72 and 77, which discuss some of the remarkable benefits supplementation has been shown to provide.
/ know that vitamins can't work properly without minerals, but do some minerals make them work more effectively than others?
Definitely. Vitamin A, for instance, works best with the minerals calcium, magnesium, phosphorus, selenium, and zinc. The B vitamins are also potentiated by these minerals, along with cobalt, copper, iron, manganese, potassium, and sodium. |
John Boik
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 A number of investigators have reported that omega-3 supplementation decreases PGE2 production by tumor cells and inhibits their growth. An EPA and DHA mixture inhibited the growth of human lung tumors in mice by 45%. The mixture reduced the content of arachidonic acid in the tumor cells by 50%, and increased the content of omega-3 fatty acids three- to fivefold. PGE2 levels in the tumor were reduced over sevenfold (De Bravo et al., 1991). EPA/DHA mixtures also decreased the production of PGE2 and decreased the growth of human prostate cancer xenografts in mice (Karmali et al., 1987). |
| The heart of the Gonzalez program consists of high doses of multiple proteolytic enzymes, although the program also includes patient-specific dietary modifications and vitamin and mineral supplementation. Gonzales has recently presented a series of case studies to the National Cancer Institute, who has encouraged him to pursue further study. With supervision from NCI, Gonzalez is currently conducting a clinical trial in New York on patients with pancreatic cancer. |
Patrick Quillin, PhD,RD,CNS
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 Human prostate cancer cells were killed at a higher rate when adriamycin (chemo drug) was combined with vitamin E at concentrations that can easily be obtained from supplementation.94 Vitamin E supplements (1600 iu/day) taken one week prior to adriamycin therapy protected 69% of patients from hair loss, which is nearly universal in adriamycin-treated patients.95 Vitamin E helped to repair kidney damage caused by adriamycin in animals.96 Vitamin E and selenium supplements in animals helped to reduce the heart toxicity from adriamycin. |
| Meydani, SN, et al, Vitamin supplementation enhances cell-mediated immunity in healthy elderly subjects, Am J Clin Nutr, 52,557-63,1990
2. Enstrom, JE, et al., Vitamin C intake and mortality among a sample of the United States population, Epidem, 3,3:194-6,1992
3. Bendich, A, et al., Dietary vitamin E requirement for optimum immune response in the rat, J Nutr;116:675-681,1986
4. Meta-analysis of survival in cancer patients using total parenteral nutrition, Ann Intern Med, 110,9, 735-7, May 1989
5. Kaminsky, M. (ed.), Hyperalimentation: a Guide for Clinicians, Marcel Dekker, NY, Oct.1985, p. |
Thomas Bartram
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 Avoid dairy products. supplementation. Vitamins A, B-complex, C. Bromelain, Zinc.
Note. See entry: COURVOISER'S LAW.
GALL-STONES. Any obstruction to the free flow of bile causes stagnation within the gallbladder. Deposits of bile pigments form (bile sand). Under chemical change, these small masses become encrusted with cholesterol and converted into gall-stones. Common in overweight middle-aged women, "fair, fat and forty". Fifteen per cent of the world's population are affected. Pain may be mistaken for heart disorder.
Stones are of two main types: cholesterol and bile pigment. |
| Vitamin and Mineral Supplementation: Because of severe drain on these food elements Multivitamins should be taken daily together with additional lOOOius Vitamin E for the disturbed circulatory system. The heart should be sustained with a preparation of the Hawthorn berry.
To be treated by or in liaison with a qualified medical practitioner.
CARDAMOM SEEDS. Elettaria cardamomum Maton. Dried ripe seeds. Volatile oil. Action. Carminative, warm and soothing to digestive system. Stomachic, Orexigenic. Antigripe. Oil is antiseptic.
Uses. Flatulence, colic, loss of appetite.
Preparations. Tea. |
| Bilberries. supplementation. Vitamin C 500mg daily. Vitamin E 400iu daily.
See also: CIRCULATION. PHLEBITIS. BRUISES, etc.
CAPRICIN. A caprylic acid formulation that facilitates absorption of calcium and magnesium. Occurs naturally in mother's milk. Antibacterial and antifungal properties. Like fish oils (EPA) this preparation, extracted from coconut, inhibits clumping of platelets and is effective against the organisms of Candida, rhodotorulla, etc. Taken with a yeast-free and sugar-free diet for Candida. |
| Vitamin A supplementation is indicated together with zinc. (Bio-availability of Vitamin A is linked with zinc levels.) Vitamin A and zinc may be applied topically in creams and ointments. Orthodox treatment: radiotherapy, chemotherapy, hysterectomy. As oestrogen can stimulate dormant cells the surgeon may wish to remove ovaries also. Whatever the decision, herbal supportive treatment may be beneficial. J.T Kent, MD, recommends Thuja and Shepherd's Purse. Agents commonly indicated: Echinacea, Wild Indigo, Thuja, Mistletoe, Wild Yam. Herbal teas may be taken with profit. |
Bill Gottlieb
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 He says to continue these levels of supplementation until the rash clears up.
See also Heat Rash; Lyme Disease
Raynaud's Disease
You can understand when Jack Frost does his nipping in the dead of winter. In fact, you almost expect it. But when you're reaching for a Labor Day beer or sitting in air-conditioning to beat the July 4th heat? That's a sign of Raynaud's disease, which leaves hands and feet cold, painful and numb at the slightest change in temperature, such as opening a refrigerator door or walking into an air-conditioned room. |
Thomas Bartram
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| Where steroid therapy is unavoidable, supplementation with Liquorice and Ginseng is believed to sustain function of the glands. Ginseng is supportive when glands are exhausted by prolonged stress. BHP (1983) recommends: Liquorice, Dandelion leaf.
Alternatives. Teas. Gotu Kola, Parsley, Liquorice root, Borage, Ginseng, Balm. Tea formula. Combine equal parts: Balm and Gotu Kola. Preparation of teas and tea mixture: 1 heaped teaspoon to each cup boiling water: infuse 5-10 minutes; 1 cup 2 to 3 times daily. Tablets/capsules. Ginseng, Seaweed and Sarsaparilla, Wild Yam, Liquorice. |
John Boik
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| The effects of nicotinamide supplementation on angiogenesis in humans has yet to be demonstrated. Nicotinamide also decreases blood flow resistance in tumors, and subsequently, lowers the intratumor vascular pressure (Lee et al, 1992). The method by which nicotinamide produces this effect is not understood. Since high vascular pressure limits the uptake of drugs by a tumor, it may be possible, under certain conditions, to use nicotinamide to increase the efficacy of anticancer drugs.
3.4 NATURAL AGENTS THAT INHIBIT ANGIOGENESIS
A number of natural agents exhibit antiangiogenic properties. |
Patricia Hausman & Judith Benn Hurley
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| The Supplement Alternative
For preventing iron deficiency, supplementation offers an alternative when you can't always manage an iron-friendly diet. Once iron-deficiency anemia develops, however, supplements are usually the only simple alternative for treating it. No matter how many iron-rich foods you choose, then, you are unlikely to take in enough iron to replenish your "iron bank" and meet your ongoing need for iron. What's more, you will probably want to get back on your feet as quickly as possible, and the extra iron in a supplement can help you do that. |
| However small the risk, we don't think it worth taking, and do recommend B12 supplementation in this case.
We're particularly concerned that vegetarian children have a reliable source of B12. Here is a story about one-year-old Edward, who didn't. It's excerpted from a report by R. C. Gambon and co-workers of Children's Hospital in Bern, Switzerland.
The 35-year-old mother had been living on a diet based on plantfood only, with strict exclusion of all animal products (meat, milk, eggs) for seven years before the birth of the twins.... Both twins were exclusively breast-fedfrom birth. |
| Every now and then, however, supplementation causes trouble for someone who decides that if some is good, more is better. So taking supplements sensibly and safely is the key to reaping their benefits. And that need not be difficult. Just keep in mind some basic facts about safe doses and signs of overuse. If signs of excessive intake are recognized early, the chances for full and rapid recovery are excellent. |
| Naturally, even the most promising studies showed that tryptophan supplementation didn't work for everyone. As for getting enough tryptophan from food to induce sleepiness, it probably can't be done. Turkey, for example, contains a good amount of tryptophan, but it is also a high-protein food. And protein makes it harder for tryptophan to get into the brain, where the sleep center is located. Other amino acids in tryptophan-containing foods also end up as competitors. It seems tryptophan prefers to play sleep fairy on its own. |
| This condition, marked by cracks around the corners of the mouth, sometimes responds to supplementation with large doses of riboflavin, a B vitamin.
Xanthomas. These yellowish nodules on the skin go hand in hand with extremely high levels of triglycerides in the blood. Dietary approaches vary from one patient to the next, depending on the particular blood fat disorder; some patients will need a very low fat diet not unlike those used for gallbladder disease; others will need a triglyceride-lowering diet. |
Dian Dincin Buchman, Ph.D.
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 When supplementation of iron is needed, do it with the help of a health care practitioner who is skilled in using nutrient remedies. Meanwhile, drink orange juice for the vitamin C and folic acid content to strengthen the capillary walls, to help reduce a profuse menstrual flow, and to increase the absorption of iron in the diet. Vitamin C foods include fruits, nuts, seeds, and buckwheat. Choose a high-potency vitamin C with flavonoids and take 1,000 mg 2 times a day. Also, cook acidic foods such as tomatoes and applesauce in cast-iron pots to leach the iron from the pot into the food. |
| Otherwise, supplementation with 500 mg of B12 has proved helpful. To further lessen the possibility of postherpetic neuralgia take daily supplements of vitamin E.
During periods of stress calm down with conscious deep breathing alternated with yoga alternate nostril breathing. With the thumb cover the right nostril and to the count of 4 breathe in through the left nostril. Breathe out through the right nostril to the count of 4. Repeat several times. This immediately reduces stress and tension and brings on a benign feeling.
The pain and misery of a shingles attack are legendary. |
John Robbins
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 A number of double-blind placebo-controlled studies have found that the frequency of antisocial behavior in juveniles is lowered significantly by appropriate supplementation.44
One remarkable double-blind, placebo-controlled study actually compared Ritalin directly with vitamin b6. Published in 1979 in the Journal of Biological Psychiatry, this study found that high doses of vitamin b6 actually did a better job than Ritalin at reducing hyperactivity.4 |
Mark Blumenthal
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 Nutr Biochem 2000;11(2):109-13. bahrman n, zivy m, damerval c, baradat p. organisation of the variability of abundant proteins in seven geographical origins of maritime pine [Pinuspinaster ait.). Theoretical & Applied Genetics 1994;88(3-4):407-l 1. bano g, raina rk, zutshi u, bedi kl, johri rk, sharma sc. effect of piperine on bioavailability and pharmacokinetics of propranolol and theophylline in healthy volunteers. Eur J Clin Pharmacol 1991 ;41 (6):615—7. baumann d, focke g, kornosoff g. phytodolor® bei patienten mit aktivierter gonarthrosse, koxanthrose bzw. schulter-arm-syndrom. |
Bill Gottlieb
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| He says to take this level of supplementation untd insomnia is no longer a problem. mm Yoga
A 30-minute meditation just before bedtime will encourage better sleep, says Alice Christensen, founder and executive director of the American Yoga Association. She suggests lying in bed to do the meditation, then rolling over and nodding off. You may even fall asleep during the meditation, she says. (Instructions for yoga meditation begin on page 153.)
If you should wake up during the night, Christensen suggests doing the yoga version of counting sheep: the complete breath (see page 152). |
Thomas Bartram
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| Vitamin E supplementation (International Journal of Fertility, Vol 28. 1983) Suggested dose: One 500iu capsule morning and evening. Retinal haemorrhage. Buckwheat tea. Vitamin C: l-3g daily. Evening Primrose oil. Red cell stimulators: Yellow Dock root, Red Clover, Gentian.
White cell stimulators: Liquorice, Ginseng (Siberian) and Korean, Goldenseal, Echinacea. Vitamins. C. D. K. P.
Minerals. Calcium, Iron, Selenium, Zinc. Note. Any new episode of bleeding (rectal, gastric, etc) in those 45 and over should be investigated in hospital. |
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